patch clamp technique

소개글

patch clamp technique에 대한 레포트

목차

1 .Introduction
2. Principle
3. Configuration
4. Procedure
5. Evaluation
6. Application
7. Limitation

본문내용

Introduction
Patch clamp
√ The Patch-clamp technique is a versatile electrophysiological tool for understanding ion channel behavior. Every cell expresses ion channels, but the most common cells to study with patch-clamp techniques include neurons, muscle fibers, cardiomyocytes, and oocytes overexpressing single ion channels.

√ An experimental method that allows electrophysiologists to hold the voltage of the cell membrane at any preset potential and to measure the currents that flow through the membrane at that potential as a function of time.

참고 자료

Cite this introduction as Cold Spring Harb Protocdoi:10.1101/pdb.top066092
Ann. Rev. Physiol. 1984.46:455-72 Copyright © 1984 by Annual Reviews Inc. All rights reserved
Patch Clamping: An Introductory Guide To Patch Clamp Electrophysiology. Areles Molleman Copyright ¶ 2003 John Wiley & Sons, Ltd. ISBN: 0-471-48685-X
1760-2734/$ - see front matter ª 2007 Published by Elsevier B.V. doi:10.1016/j.jvc.2007.02.001