[유기화학실험]benzoin condensation

소개글

name reaction중 이합체 반응 영역에 대한 실험입니다.
축합반응을 통해 여러 축합반응 adol, 클라이젠 반응등이 있겠지만 생소히 다둘수 없는 benzoin을 합성해보는 실험레포트 입니다.

축합반응중 benzalacetophenone의(chalcone) 알돌반응에 대한 한글파일도 있으니 참고 바랍니다.

자세한 설명을 해놓은 한글 파일도 있으니 많은 참고바랍니다!

목차

Purpose
Condensation Reaction
Preparation of α-hydroxyketones
Cyanide-catalyzed Reaction
Mechanism of Benzoin Condensation
Reagents & Apparatus
Methods
References

본문내용

Benzoin을 합성하고 유기물질을 만들 수 있다.
시안화 나트륨(NaCN)이나 시안화칼륨(KCN)의 촉매 작용으로 일어나는 두 방향족 알데히드 분자의 이합체 반응을 알아본다.

The Benzoin condensation is a condensation reaction between two aromatic aldehydes, especially benzaldehyde, that is catalyzed by cyanide anion. The reaction product is an aromatic acyloin with benzoin as the parent compound . An early version of the reaction was developed in 1832 by Justus von Leibig and Friederich Woehler during their research on oil of bitter almond. The catalytic version of the reaction was developed by Nikolay Zinin in the late 1830s. The reaction mechanism for this organic reaction was proposed in 1903 by A. J. Lapworth

참고 자료

Strategic Applications of Named Reactions in Organic Synthesis, Kurti(2005), p54
Chemistry - Named Organic Reactions 2Nd Ed, Thomas Laue and Andreas Plagens(2005), p36~37