Duodenal Ulcer
- 최초 등록일
- 2011.02.26
- 최종 저작일
- 1997.01
- 10페이지/ MS 파워포인트
- 가격 1,000원
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Duodenal Ulcer의 전반적 내용
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DUs occur most often in the first portion of duodenum (>95%), with ~90% located within 3 cm of the pylorus.
Ulcer: usually less than 1 cm in diameter but can occasionally reach 36 cm (giant ulcer). sharply demarcated, with depth at times reaching the muscularis propria.
Malignant DUs are extremely rare.
H. pylori and NSAID-induced injury
H. pylori
Many acid secretory abnormalities: H. pylori ?
Reduced bicarbonate secretion
NSAID-induced injury
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Many acid secretory abnormalities have been described in DU patients. Of these, average basal and nocturnal gastric acid secretion appears to be increased in DU patients as compared to controls; however, the level of overlap between DU patients and control subjects is substantial. The reason for this altered secretory process is unclear, but H. pylori infection may contribute. Accelerated gastric emptying of liquids has been noted in some DU patients, but its role in DU formation, if any, is unclear. Bicarbonate secretion is significantly decreased in the duodenal bulb of patients with an active DU as compared to control subjects. H. pylori infection may also play a role in this process (see below).
Abdominal pain
Epigastric pain
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